Neuromodulators are medicines like Botox® and Xeomin® which are used in aesthetic medicine to temporarily relax the muscles that cause moderate to severe wrinkling. Most commonly they are used to treat frown lines, crow’s feet, and forehead wrinkles in adults. They are also used for a number of other medical conditions such as hyperhidrosis (excessive sweating), TMJ, migraines, and severe muscle spasms. The injectable contains a purified protein that relaxes the small muscles that cause excessive contraction leading to wrinkles and other conditions.